In safety studies selamectin solution was applied at 1 3 5 and 10 times the recommended dose to six week old kittens.
Revolution selamectin for dogs side effects.
Selamectin is however safe to use in pregnant or lactating pets.
No adverse reactions were observed.
Revolution is the brand name for the generic drug selamectin.
Like other drugs it does carry the risk of certain side effects.
Selamectin is a synthetic ingredient that gets into the parasite s system and replaces an important amino acid that controls the release of chloride into the bloodstream.
Sarolaner one of the ingredients in revolution plus is a member of the isoxazoline class which has been associated with adverse reactions such as tremors ataxia and seizures.
As a result the chloride enters the parasite s nerve cells causing paralysis and death.
However it should be avoided if at all possible in animals that are younger than 6 weeks of age or that are underweight.
Reading the studies on revolution side effects it does talk about some animals having adverse effects.
Selamectin is the active ingredient and is a neurotoxin which attacks the central nervous system it is not meant to cross the brain blood barrier in mammals but does in fleas etc.
The main ingredient in revolution is selamectin.
Selamectin is generally considered safe for use in animals of all ages and types.
Selamectin is a topical agent and temporary irritation and hair loss at the site of application is possible.
Use with caution in cats with a history of neurologic disorders.
Vomiting loose stools diarrhea with or without blood anorexia lethargy salivation tachypnea and muscle tremors are other revolution side effects in dogs listed but they are claimed by pfizer s insert to be rare 0 5 of 1743 cats and dogs treated.
Reported side effects in clinical trials included lethargy and anorexia.
There have been reports of a few collies drooling and staggering when overdosed with.
Although it is applied to the skin revolution has a holistic effect that targets both internal and external parasites.
Selamectin solution also was administered at 3 times the recommended dose to heartworm infected dogs and no adverse effects were observed.
Side effects and risks of selamectin.
The administration of selamectin may result in oily stiff discolored or powdery hair or skin at the administration site.
Ingredients in revolution for dogs.